Is Canine Epilepsy Associated with Gut Dybiosis?

Is Canine Epilepsy Associated with Gut Dysbiosis?

Participate from home!

The Companion Animal Epilepsy Research program at NC State University College of Veterinary Medicine is recruiting for a new clinical trial to determine whether dogs with idiopathic epilepsy have alterations in their gut microbial population. Our study team is looking for households with an epileptic dog and an unaffected dog to compare the bacterial populations within their gastrointestinal tract. Feces will be collected from both dogs to compare their gut microbiome.


  • Owners must be willing to collect a one-time fecal sample from both dogs and send samples to NCSU CVM (pre-paid shipping). Owners will also be required to complete a brief online questionnaire at the time of sample collection.


  • Free fecal floatation to examine for parasites
  • All study materials, including shipping, will be covered by the study
  • Participation will provide additional information about epilepsy that may help your dog or other animals in the future


  • Households must have one dog with epilepsy and one unaffected dog
  • Epileptic dog must have presumptive diagnosis of idiopathic epilepsy based on seizure onset between 6 months and 6 years of age, and not be on seizure medication or be on phenobarbital alone
  • Both dogs must not be on any other medications aside from monthly preventatives
  • Dogs must be fed the same diet

For more information or to enroll your dogs, contact Julie Nettifee, RVT, BS, VTS (Neurology):